Dynameomics: A Comprehensive Database of Protein Dynamics
نویسندگان
چکیده
منابع مشابه
Dynameomics: a comprehensive database of protein dynamics.
The dynamic behavior of proteins is important for an understanding of their function and folding. We have performed molecular dynamics simulations of the native state and unfolding pathways of over 2000 protein/peptide systems (approximately 11,000 independent simulations) representing the majority of folds in globular proteins. These data are stored and organized using an innovative database a...
متن کاملDynameomics: a multi-dimensional analysis-optimized database for dynamic protein data.
The Dynameomics project is our effort to characterize the native-state dynamics and folding/unfolding pathways of representatives of all known protein folds by way of molecular dynamics simulations, as described by Beck et al. (in Protein Eng. Des. Select., the first paper in this series). The data produced by these simulations are highly multidimensional in structure and multi-terabytes in siz...
متن کاملDesign and Implementation of a Comprehensive Database of the Written Heritage of Science and Technology
Purpose: This study aims to design and implement a comprehensive database of the written heritage of science and technology in the Regional Information Center for Science and Technology (RICeST) and determine the metadata elements required to describe the manuscripts. Method: This study was carried out by the content analysis method to identify the metadata elements needed to describe the coll...
متن کاملA comprehensive and non-redundant database of protein domain movements
MOTIVATION The current DynDom database of protein domain motions is a user-created database that suffers from selectivity and redundancy. The aim of the analysis presented here was to overcome both these limitations and to produce both a comprehensive and a non-redundant description of domain movements from structures stored in the current protein data bank. RESULTS A multi-step procedure is ...
متن کاملPIBASE: a comprehensive database of structurally defined protein interfaces
MOTIVATION In recent years, the Protein Data Bank (PDB) has experienced rapid growth. To maximize the utility of the high resolution protein-protein interaction data stored in the PDB, we have developed PIBASE, a comprehensive relational database of structurally defined interfaces between pairs of protein domains. It is composed of binary interfaces extracted from structures in the PDB and the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Structure
سال: 2010
ISSN: 0969-2126
DOI: 10.1016/j.str.2010.01.012